Stanford Scientists Unveil Breakthrough That Could Eliminate the Need for Knee Replacements by Regrowing Cartilage with a Single Injection

Stanford Medicine published a landmark study in Science (June 12, 2026) showing that blocking the aging enzyme 15-PGDH completely reverses cartilage loss in old mice, prevents post-injury arthritis, and regenerates human knee tissue from replacement surgeries. Here is the full breakthrough.